Knick-knack PADIMAC

Getting a Knack for NAC: N-Acetyl-Cysteine.

N-acetyl-cysteine, N-acetylcysteine, N-acetyl cysteine, and N-acetyl-L-cysteine are all designations for the same compound, which is abbreviated as NAC. NAC is a precursor to the amino acid cysteine, which ultimately plays two key metabolic roles. Through its metabolic contribution to glutathione production, cysteine participates in the general antioxidant activities of the body. Through its ro...

Editorial: Nck has a knack for T cell differentiation.

Introduction Nck is a ubiquitous SH2/SH3 adaptor protein that acts as a scaffold, connecting receptor tyrosine kinases in the plasma membrane with cytoplasmic signaling proteins involved in rearrangement of the actin cytoskeleton. Therefore, Nck is an important player in actin-guided axonal growth in neurons and in kidney podocyte mobility [1]. However, Nck also mediates the activation of signa...

KNACK-2002: a Richly Annotated Corpus of Dutch Written Text

In this paper, we introduce the annotated KNACK-2002 corpus of Dutch written text. The corpus features five different annotation layers, ranging from the annotation of morphological boundaries at the word level, over the annotation of part-of-speech tags and phrase chunks at the syntactic level to the annotation of named entities at the semantic level and coreferential relations at the discours...

The Knick and Die Charité: Historical Hospital Series and the History of Medicine

Science and Culture: Armed with a knack for patterns and symmetry, mathematical sculptors create compelling forms.

When he was growing up in the 1940s and 1950s, teachers and parents told Helaman Ferguson he would have to choose between art and science. The two fields inhabited different realms, and doing one left no room for the other. “If you can do science and have a lick of sense, you’d better,” he recalled being told, in a 2010 essay in the Notices of the American Mathematical Society (1). “Artists sta...